Smart mechanochemistry: optimizing amino acid acylation with one factor at a time, design of experiments and machine learning methods
A mechanochemical acylation of unprotected amino acids was optimized with three different methods: OFAT, DoE and BO.
Authors
- Olivia Giani (ORCID: https://orcid.org/0000-0002-1833-2324)
- Xavier Bantreil (ORCID: https://orcid.org/0000-0002-2676-6851)
- Frédéric Lamaty (ORCID: https://orcid.org/0000-0003-2213-9276)
- Nicolas Pétry (ORCID: https://orcid.org/0000-0002-9785-498X)
- Julien Pinaud (ORCID: https://orcid.org/0000-0003-4446-3771)
- Matthieu Lavayssiere (ORCID: https://orcid.org/0000-0003-2965-4203)
- Adrien Gallego (ORCID: https://orcid.org/0009-0009-2152-2258)
Institutions
- École Nationale Supérieure de Chimie de Montpellier (FR)
- Centre National de la Recherche Scientifique (FR)
- Institut Universitaire de France (FR)
- Institut Charles Gerhardt Montpellier (FR)
- Institut de Chimie (FR)
- Institut des Biomolécules Max Mousseron (FR)
Publication Details
- Journal
- RSC Mechanochemistry
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1039/d5mr00096c
- Citations
- 1
- Primary Topic
- Crystallography and molecular interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- Agence Nationale de la Recherche
- Centre National de la Recherche Scientifique
- Université de Montpellier