Optimizing Human Nasal Turbinate Stem Cell Dosage for the Effective Treatment of Empty Nose Syndrome
These findings demonstrate that hNTSC-based therapy effectively promotes epithelial regeneration in ENS, with an optimal therapeutic dose identified at 1×107 cells/mL. This study highlights the potential clinical application of stem cell therapy for ENS and underscores the need for precise dose optimization to maximize therapeutic outcomes.
Authors
- David W. Jang (ORCID: https://orcid.org/0000-0003-4200-7174)
- Yun Jin Kang (ORCID: https://orcid.org/0000-0002-7677-4219)
- Mi Hyun Lim (ORCID: https://orcid.org/0009-0009-7576-5247)
- Do Hyun Kim (ORCID: https://orcid.org/0000-0002-9248-5572)
- Sung Won Kim (ORCID: https://orcid.org/0000-0002-8981-2536)
- Jae Yoon Lee (ORCID: https://orcid.org/0000-0003-4973-0859)
- Dan Bi Park (ORCID: https://orcid.org/0009-0006-1223-9141)
- Simon Yoo (ORCID: https://orcid.org/0000-0002-7713-2103)
Institutions
- Duke University (US)
- The Catholic University of Korea Yeouido St. Mary's Hospital (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Journal of rhinology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.18787/jr.2025.00021
- Primary Topic
- Nasal Surgery and Airway Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00