Clinicopathologic characteristics and prognostic outcomes of surgically treated neuroendocrine cervical carcinoma: A single institution retrospective analysis

NECC is a highly aggressive subtype of cervical cancer, frequently associated with HPV infection-particularly HPV18-and characterized by a high risk of lymph node metastasis and poor prognosis. NECC often coexists with other malignancies. ThinPrep cytology test (TCT) combined with HPV testing may be a potential method for early detection. Surgical resection followed by adjuvant chemotherapy and/or radiotherapy may be an effective treatment strategy for early-stage NECC. FIGO stage and the extent of multiple lymph node metastases are key prognostic factors.