Designing Novel NMDA Receptor Antagonists for Ischemic Stroke: A3D-QSAR and Molecular Dynamics Simulation Approach

These findings provide a rational framework for the development of selective NMDA receptor antagonists with improved safety and efficacy profiles.

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Publication Details

Journal
Current Topics in Medicinal Chemistry
Published
2025-11-28
DOI
https://doi.org/10.2174/0115680266412043251124065339
Primary Topic
Neuroscience and Neuropharmacology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Designing Novel NMDA Receptor Antagonists for Ischemic Stroke: A3D-QSAR and Molecular Dynamics Simulation Approach

Boru Hou, Changfa Fan, Xiaolin Jiang, Zhuangzhuang Wan
Current Topics in Medicinal Chemistry
Neuroscience and Neuropharmacology Research
article

Designing Novel NMDA Receptor Antagonists for Ischemic Stroke: A3D-QSAR and Molecular Dynamics Simulation Approach

Boru Hou, Changfa Fan, Xiaolin Jiang, Zhuangzhuang Wan
article en

Abstract

These findings provide a rational framework for the development of selective NMDA receptor antagonists with improved safety and efficacy profiles.

Current Topics in Medicinal ChemistryVol. 26
Gansu University of Traditional Chinese Medicine (CN), Lanzhou University Second Hospital (CN), Lanzhou University (CN)
Openalex Percentile: Top 60%
Neuroscience and Neuropharmacology Research
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