Molecular, biofilm and motility characterization of Acinetobacter baumannii isolated from a neonatal intensive care unit at a children’s hospital in South China
This NICU outbreak was driven by CRAB ST195 harboring a conserved resistome. Strain-specific differences in biofilm formation and motility under antibiotic stress highlight the interplay between genetic lineage and phenotypic adaptability. Levofloxacin demonstrates dual anti-biofilm and anti-motility effects, which could guide targeted infection control strategies against high-risk <i>A. baumannii</i> clones.
Authors
- Cai Dan-wei
- Zelin Yu (ORCID: https://orcid.org/0000-0002-5190-2392)
- Xiaolong Luo (ORCID: https://orcid.org/0000-0002-9939-2766)
- Zejian Kuang
- Xiao-Bing Hong (ORCID: https://orcid.org/0000-0001-5912-7469)
- Hongbo Fu (ORCID: https://orcid.org/0000-0002-0284-726X)
- Yuebin Wu (ORCID: https://orcid.org/0000-0002-8581-3275)
- Yanqiong Zhou
- Wu Xiuming
Institutions
- Shantou University (CN)
- Second Affiliated Hospital of Shantou University Medical College (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fcimb.2025.1705282
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00