Structural and genomic insights into erythromycin and clindamycin resistance of group B Streptococcus isolates in rural West Virginia, United States
Our data demonstrate that the 80.0% rate of erythromycin and 70.8% of clindamycin resistance in WV is higher than the national average of 61.7 and 52.5%, respectively, while being widespread across a variety of clinical specimens (urine, throat, respiratory tract, blood, foot ulcers, perisplenic fluid, various wounds, and the rectovaginal area). Providers should be aware of the current threat of antibiotic resistance, especially in "primary care deserts" existing in rural areas such as WV.
Authors
- Lillie M. Powell (ORCID: https://orcid.org/0000-0003-1392-4635)
- Soo Jeon Choi (ORCID: https://orcid.org/0000-0002-7030-7230)
- Adam C. Palmer (ORCID: https://orcid.org/0000-0001-5028-7028)
- Austin Smith (ORCID: https://orcid.org/0000-0002-3029-4682)
- Sławomir Łukomski (ORCID: https://orcid.org/0000-0002-5159-1838)
- Rita Berisio (ORCID: https://orcid.org/0000-0001-5025-6483)
- Ryan Demkowicz (ORCID: https://orcid.org/0000-0002-5402-1873)
Institutions
- West Virginia University (US)
- Institute of Biostructure and Bioimaging (IT)
- National Research Council (IT)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fmicb.2025.1686688
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centers for Disease Control and Prevention