Neoadjuvant chemoradiotherapy plus programmed cell death protein-1 blockade versus chemoradiotherapy alone for muscle-invasive bladder cancer: a real-world comparative study
NACRT combined with PD-1 blockade significantly improved PCRR without increasing toxicity in patients with MIBC. These findings support conducting a prospective single-arm phase II multicenter trial to confirm potential long-term survival benefits.
Authors
- Fan Zhang (ORCID: https://orcid.org/0000-0003-2834-2646)
- Jun Ouyang (ORCID: https://orcid.org/0000-0003-1509-0558)
- Yipeng Yu
- Chenkai Zhang (ORCID: https://orcid.org/0009-0004-1583-0506)
- Jingsuo Wang
- Zhiyu Zhang (ORCID: https://orcid.org/0000-0002-4783-0082)
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fimmu.2025.1711690
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Program of Suzhou