Structural brain changes in subacute spinal cord injury: an analysis of diffusion kurtosis imaging and diffusion tensor imaging metrics with clinical correlation
Structural changes in the corpus callosum may reflect impaired interhemispheric communication, linked to reduced functional independence after SCI. DTI and DKI could serve as complementary tools for identifying brain-based biomarkers, potentially informing recovery trajectories.
Authors
- Alexander Leemans (ORCID: https://orcid.org/0000-0002-9306-6126)
- Ernst Christiaanse
- Anke Scheel‐Sailer (ORCID: https://orcid.org/0000-0003-3820-6664)
- Alberto De Luca (ORCID: https://orcid.org/0000-0002-2553-7299)
- Patrik O. Wyss (ORCID: https://orcid.org/0000-0002-6057-2727)
- Giuseppe A. Zito (ORCID: https://orcid.org/0000-0002-5027-884X)
- Rajeev Verma (ORCID: https://orcid.org/0000-0002-7827-1834)
- Jothini Sritharan (ORCID: https://orcid.org/0009-0008-4549-6229)
Institutions
- University of Lucerne (CH)
- University Hospital of Bern (CH)
- University Medical Center Utrecht (NL)
- Swiss Paraplegic Center (CH)
- Swiss Paraplegic Research (CH)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fnins.2025.1652416
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00