Double-stranded RNA antiviral signature in early multiple sclerosis
Our findings identify increased plasma viral dsRNA coupled with reduced anti-dsRNA IgM antibody levels as potential biomarkers for a subpopulation of early MS patients and indicate a dysregulated anti-viral immune response.
Authors
- Urania Georgopoulou (ORCID: https://orcid.org/0000-0002-2784-3695)
- Peggy Lymberi
- Maria Anagnostouli (ORCID: https://orcid.org/0000-0001-8934-670X)
- Lesley Probert (ORCID: https://orcid.org/0000-0002-5931-2880)
- Vasileios Gouzouasis
- Antonis Giannakakis (ORCID: https://orcid.org/0000-0003-2975-0326)
- Ioannis Sarrigeorgiou (ORCID: https://orcid.org/0000-0002-3545-0330)
- Margaritis Tsifintaris (ORCID: https://orcid.org/0000-0001-8603-3767)
- Nikos Markoglou
Institutions
- Democritus University of Thrace (GR)
- National and Kapodistrian University of Athens (GR)
- Pasteur Hellenic Institute (GR)
- Eginition Hospital (GR)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fmicb.2025.1706133
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00