Differential antioxidant enzyme profiles reveal early molecular signatures of virulence in Trypanosoma cruzi DTU-TcI and DTU-TcVI strains
Enhanced early expression of antioxidant enzymes appears to correlate with <i>T. cruzi</i> virulence and persistence, suggesting a potential role for these molecules as biomarkers or therapeutic targets. These observations may help clarify strain-specific mechanisms contributing to Chagas disease pathogenesis.
Authors
- Maritza Calderón Sánchez
- Alexandre F. Marques (ORCID: https://orcid.org/0000-0001-9416-3465)
- Daniella Castanheira Bartholomeu (ORCID: https://orcid.org/0000-0003-0974-7357)
- Edward Valencia Ayala (ORCID: https://orcid.org/0000-0002-5318-5526)
- Agostino Riva (ORCID: https://orcid.org/0000-0003-3171-3049)
- J. Cunha
Institutions
- Universidade Federal de Minas Gerais (BR)
- National University of San Marcos (PE)
- Universidad Peruana Cayetano Heredia (PE)
- Universidad de San Martín de Porres (PE)
- University of Southern Mississippi (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fcimb.2025.1664827
- Primary Topic
- Trypanosoma species research and implications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- World Bank Group