Bridge to recovery: A case of V-V ECMO following V-A ECMO in Eisenmenger syndrome
We report a case of successful treatment for a severe acute pulmonary hypertension crisis in a patient with Eisenmenger syndrome (ES) associated with patent ductus arteriosus following trauma-related spine surgery, utilizing both veno-arterial (V-A) and veno-venous (V-V) ECMO. The patient's clinical course was complicated by right ventricular failure amid a pulmonary hypertensive crisis, necessitating V-A ECMO support. Persistent hypoxia, despite improved right heart function, warranted transition to V-V ECMO. This case demonstrates that peripheral V-A ECMO can be safely employed to decompress the right heart in the presence of a significant PDA shunt. Furthermore, weaning from ECMO in these patients requires a much higher hematocrit in order to compensate for the chronic hypoxia.
Authors
- Ningxin Wan
- Charles A. Mack (ORCID: https://orcid.org/0000-0001-8142-9818)
- Berhane Worku (ORCID: https://orcid.org/0000-0003-0135-580X)
- Iosif Gulkarov (ORCID: https://orcid.org/0000-0002-2687-7340)
- A Riccio (ORCID: https://orcid.org/0000-0001-8392-533X)
- Nicole Palmer (ORCID: https://orcid.org/0000-0002-0231-1158)
- Leonard N. Girardi (ORCID: https://orcid.org/0000-0003-3230-4239)
- Ankur Srivastava (ORCID: https://orcid.org/0009-0001-0882-4691)
- Linjia Jia
- Nathnael Feleke (ORCID: https://orcid.org/0009-0002-9372-9505)
Institutions
- NewYork–Presbyterian Hospital (US)
- Cornell University (US)
- New York Hospital Queens (US)
- Presbyterian Hospital (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Perfusion
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1177/02676591251406127
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00