Bridge to recovery: A case of V-V ECMO following V-A ECMO in Eisenmenger syndrome

We report a case of successful treatment for a severe acute pulmonary hypertension crisis in a patient with Eisenmenger syndrome (ES) associated with patent ductus arteriosus following trauma-related spine surgery, utilizing both veno-arterial (V-A) and veno-venous (V-V) ECMO. The patient's clinical course was complicated by right ventricular failure amid a pulmonary hypertensive crisis, necessitating V-A ECMO support. Persistent hypoxia, despite improved right heart function, warranted transition to V-V ECMO. This case demonstrates that peripheral V-A ECMO can be safely employed to decompress the right heart in the presence of a significant PDA shunt. Furthermore, weaning from ECMO in these patients requires a much higher hematocrit in order to compensate for the chronic hypoxia.

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Publication Details

Journal
Perfusion
Published
2025-11-27
DOI
https://doi.org/10.1177/02676591251406127
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Bridge to recovery: A case of V-V ECMO following V-A ECMO in Eisenmenger syndrome

Ningxin Wan, Charles A. Mack, Berhane Worku, Iosif Gulkarov et al.
Perfusion
Mechanical Circulatory Support Devices
article

Bridge to recovery: A case of V-V ECMO following V-A ECMO in Eisenmenger syndrome

Ningxin Wan, Charles A. Mack, Berhane Worku, Iosif Gulkarov, A Riccio, Nicole Palmer, Leonard N. Girardi, Ankur Srivastava, Linjia Jia, Nathnael Feleke
article en

Abstract

We report a case of successful treatment for a severe acute pulmonary hypertension crisis in a patient with Eisenmenger syndrome (ES) associated with patent ductus arteriosus following trauma-related spine surgery, utilizing both veno-arterial (V-A) and veno-venous (V-V) ECMO. The patient's clinical course was complicated by right ventricular failure amid a pulmonary hypertensive crisis, necessitating V-A ECMO support. Persistent hypoxia, despite improved right heart function, warranted transition to V-V ECMO. This case demonstrates that peripheral V-A ECMO can be safely employed to decompress the right heart in the presence of a significant PDA shunt. Furthermore, weaning from ECMO in these patients requires a much higher hematocrit in order to compensate for the chronic hypoxia.

Perfusion
NewYork–Presbyterian Hospital (US), Cornell University (US), New York Hospital Queens (US), Presbyterian Hospital (US), Weill Cornell Medicine (US)
Openalex Percentile: Top 64%
Mechanical Circulatory Support Devices
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Bridge to recovery: A case of V-V ECMO following V-A ECMO in Eisenmenger syndrome — Ningxin Wan, Charles A. Mack, et al. · Perfusion (2025) | TGRS Research Map | TGRS