Integrated Spatiotemporal and Correlative Analysis of ATP-Related Signaling Components in Lens Development

Integrated bioinformatic and experimental evidence indicate that ATP signaling components display distinct spatiotemporal expression patterns and possible associations with multiple functional pathways. In addition, various purinergic receptor subtypes may be implicated in coordinated and potentially diverse processes during lens development and the maintenance of transparency. Together, these correlative findings provide insights into the involvement of ATP and purinergic signaling in lens morphogenesis and homeostasis.