Unilateral telangiectasia macularis eruptiva perstans: A rare case of adult-onset cutaneous mastocytosis

Here, we report a case of a 35-year-old woman who presented to the dermatology outpatient clinic with complaints of reddish to slightly hyperpigmented lesions over the left flank region for the past 3 months.e lesions were asymptomatic and initially involved small areas but became more noticeable over time as they increased in size and color intensity.She reported episodic flushing and palpitations but denied other systemic symptoms such as abdominal pain, diarrhea, syncope, itching, wheal, or anaphylaxis.On clinical examination, we observed diffuse erythematous macules with telangiectasias distributed over the left side of the abdomen [Figure 1a].e lesions exhibited a positive Darier's sign, characterized by a wheal flare response upon rubbing [Figure 1b].No hepatosplenomegaly, lymphadenopathy, or other systemic manifestations were noted.Clinical differentials included telangiectasia

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Publication Details

Journal
Journal of Skin and Sexually Transmitted Diseases
Published
2025-11-28
DOI
https://doi.org/10.25259/jsstd_95_2025
Primary Topic
Mast cells and histamine
Type
article
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article

Unilateral telangiectasia macularis eruptiva perstans: A rare case of adult-onset cutaneous mastocytosis

Yasmeen Jabeen Bhat, Mohd Shurjeel Ul Islam, Y Sultan
Journal of Skin and Sexually Transmitted Diseases
Mast cells and histamine
article

Unilateral telangiectasia macularis eruptiva perstans: A rare case of adult-onset cutaneous mastocytosis

Yasmeen Jabeen Bhat, Mohd Shurjeel Ul Islam, Y Sultan
article en

Abstract

Here, we report a case of a 35-year-old woman who presented to the dermatology outpatient clinic with complaints of reddish to slightly hyperpigmented lesions over the left flank region for the past 3 months.e lesions were asymptomatic and initially involved small areas but became more noticeable over time as they increased in size and color intensity.She reported episodic flushing and palpitations but denied other systemic symptoms such as abdominal pain, diarrhea, syncope, itching, wheal, or anaphylaxis.On clinical examination, we observed diffuse erythematous macules with telangiectasias distributed over the left side of the abdomen [Figure 1a].e lesions exhibited a positive Darier's sign, characterized by a wheal flare response upon rubbing [Figure 1b].No hepatosplenomegaly, lymphadenopathy, or other systemic manifestations were noted.Clinical differentials included telangiectasia

Journal of Skin and Sexually Transmitted DiseasesVol. 7
Government Medical College (IN)
Openalex Percentile: Top 58%
Mast cells and histamine
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Unilateral telangiectasia macularis eruptiva perstans: A rare case of adult-onset cutaneous mastocytosis — Yasmeen Jabeen Bhat, Mohd Shurjeel Ul Islam, et al. · Journal of Skin and Sexually Transmitted Diseases (2025) | TGRS Research Map | TGRS