Characterizing heterogeneous cis-regulatory elements in gene regulatory programs associated with breast cancer
This study provides a valuable resource for future epigenetic research on BC and highlights the diverse regulatory landscape within or among tumor(s), suggesting that cCREs regulate intra- and intertumor heterogeneity.
Authors
- Reo Maruyama (ORCID: https://orcid.org/0000-0001-7166-5964)
- Liying Yang (ORCID: https://orcid.org/0000-0002-4336-9014)
- Toshimi Takano (ORCID: https://orcid.org/0000-0002-8417-5291)
- Tomo Osako (ORCID: https://orcid.org/0000-0001-9250-4035)
- Shinji Ohno
- Kohei Kumegawa (ORCID: https://orcid.org/0000-0003-3732-2874)
- Natsue Uehiro (ORCID: https://orcid.org/0000-0002-6940-448X)
- Takayuki Ueno (ORCID: https://orcid.org/0000-0002-9080-9377)
- Yukinori Ozaki (ORCID: https://orcid.org/0000-0002-8064-648X)
- Kazutaka Otsuji (ORCID: https://orcid.org/0000-0002-5688-5536)
- Tomoyoshi Nakadai
- Chikako Takahata
- Seiichi Mori (ORCID: https://orcid.org/0000-0001-8569-4504)
- Yurie Haruyama
- Yōko Takahashi (ORCID: https://orcid.org/0000-0002-6235-4184)
- Satoshi Fujii
- Tetsuo Noda
- Sumito Saeki
- Chikahide Hori
Institutions
- Japanese Foundation For Cancer Research (JP)
- Yokohama City University (JP)
Publication Details
- Journal
- Genome Medicine
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s13073-025-01562-1
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mochida Memorial Foundation for Medical and Pharmaceutical Research
- Yasuda Memorial Medical Foundation
- Japan Society for the Promotion of Science
- JST-Mirai Program