Clinical characteristics of myasthenia gravis patients with coexistence of AChR and titin antibodies

This study provides the first systematic characterization of the clinical profile of AChR-Ab<sup>+</sup>/Titin-Ab<sup>+</sup> myasthenia gravis patients in Southwest China. Our findings indicate that dual antibody-positive MG patients are more prone to generalized disease involvement and have a higher susceptibility to thyroid dysfunction.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-11-28
DOI
https://doi.org/10.3389/fneur.2025.1679404
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
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article

Clinical characteristics of myasthenia gravis patients with coexistence of AChR and titin antibodies

Xujun Chu, Qi‐Jie Zhang, Jianjian Bao, Jia Liu et al.
Frontiers in Neurology
Myasthenia Gravis and Thymoma
article

Clinical characteristics of myasthenia gravis patients with coexistence of AChR and titin antibodies

Xujun Chu, Qi‐Jie Zhang, Jianjian Bao, Jia Liu, Siqi Wang, Qian Fang, Yan Zheng, Kang Du, Shanshan Wu, Difang Shi, Weiwei Xiao
article en

Abstract

This study provides the first systematic characterization of the clinical profile of AChR-Ab<sup>+</sup>/Titin-Ab<sup>+</sup> myasthenia gravis patients in Southwest China. Our findings indicate that dual antibody-positive MG patients are more prone to generalized disease involvement and have a higher susceptibility to thyroid dysfunction.

Frontiers in NeurologyVol. 16
Kunming Medical University (CN), Qujing Normal University (CN), Shandong Provincial Hospital (CN), Shandong First Medical University (CN)
Openalex Percentile: Top 49%
Myasthenia Gravis and Thymoma
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