Tumor-associated macrophage expression in colorectal adenomas and carcinomas: relationship to Helicobacter pylori infection

The expression of CD68<sup>+</sup>CD163<sup>+</sup> and CD68<sup>+</sup>CD86<sup>+</sup> TAMs change dynamically with the progression of colorectal lesions. These changes are influenced by <i>H.pylori</i> infection, adenoma size, tumor differentiation, and patient metabolic status.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-11-28
DOI
https://doi.org/10.3389/fonc.2025.1649619
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Tumor-associated macrophage expression in colorectal adenomas and carcinomas: relationship to Helicobacter pylori infection

JinRong Wang, Yueyong Zhu, Yuan Zhu, Wen‐Ming Wang
Frontiers in Oncology
Immune cells in cancer
article

Tumor-associated macrophage expression in colorectal adenomas and carcinomas: relationship to Helicobacter pylori infection

JinRong Wang, Yueyong Zhu, Yuan Zhu, Wen‐Ming Wang
article en

Abstract

The expression of CD68<sup>+</sup>CD163<sup>+</sup> and CD68<sup>+</sup>CD86<sup>+</sup> TAMs change dynamically with the progression of colorectal lesions. These changes are influenced by <i>H.pylori</i> infection, adenoma size, tumor differentiation, and patient metabolic status.

Frontiers in OncologyVol. 15
Fujian Medical University (CN), Anhui Business College (CN), First Affiliated Hospital of Fujian Medical University (CN), West Anhui University (CN)
Openalex Percentile: Top 58%
Immune cells in cancer
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