A study on the association of apolipoprotein E with oxidative stress markers, neurological function, and cognitive impairment following traumatic brain injury
ApoE exhibits an injury-severity-dependent increase during the early stage of TBI, and its levels are closely associated with oxidative stress imbalance and cognitive impairment. These findings suggest that ApoE may play a critical role in both the pathological progression and neural repair following TBI.
Authors
- Kun Chen (ORCID: https://orcid.org/0000-0003-0507-7640)
- Haoyang Wang (ORCID: https://orcid.org/0009-0002-1700-5919)
- Lijun Hou (ORCID: https://orcid.org/0000-0001-9877-1599)
Institutions
- Shanghai Changzheng Hospital (CN)
- Chaozhou Central Hospital (CN)
- 181st Hospital of Chinese People's Liberation Army (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fneur.2025.1692712
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00