Human papillomavirus seminal carriage alters virome diversity and male fertility: a case-control study
The male seminal virome mainly comprises viruses from the Papillomaviridae, Herpesviridae and Polyomaviridae families. The correlation between viral diversity and sperm parameters in HPV-positive patients suggests that HPV-specific interactions within the seminal virome are responsible for variations in sperm parameters. Hence, alterations in the seminal virome (due mostly to HPV infection) might impact sperm parameters and thus male fertility.
Authors
- Rosalie Cabry‐Goubet
- Armin Priam
- Baptiste Demey (ORCID: https://orcid.org/0000-0002-5456-6654)
- Aurélien Aubry (ORCID: https://orcid.org/0009-0007-0842-5723)
- Dorian Bosquet
- Etienne Brochot
- Elissa Kansou
Institutions
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Périnatalité & Risques Toxiques (FR)
- Université de Picardie Jules Verne (FR)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s12958-025-01488-8
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00