Assessing the radiation-induced bystander effect in radionuclide therapy using targeted radiopharmaceuticals
This study elucidates the complex interplay of direct and bystander effects in targeted radionuclide therapy, demonstrating that the therapeutic efficacy and cellular response depend on the specific radionuclide and its energy profile. The findings emphasize the need for further exploration of RIBBEs to optimize radionuclide-based cancer therapies to enhance their clinical efficacy.
Authors
- Poonam Jagasia
- Archana Mukherjee (ORCID: https://orcid.org/0000-0003-3068-1890)
- Rohit Sharma (ORCID: https://orcid.org/0000-0003-4534-1055)
- Suman Kumar Singh (ORCID: https://orcid.org/0000-0002-0358-7922)
Institutions
- Bhabha Atomic Research Centre (IN)
- Homi Bhabha National Institute (IN)
- Bhabha Atomic Research Center Hospital (IN)
Publication Details
- Journal
- EJNMMI Radiopharmacy and Chemistry
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s41181-025-00393-0
- Citations
- 1
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36