Value of the Serum Dexamethasone Determination for the Diagnosis of Mild Autonomous Cortisol Secretion

Up to 4% of the patients with MACS diagnosis based on a DST > 1.8 µg/dl do not achieve enough dexamethasone levels to suppress the hypothalamic pituitary adrenal axis, suggesting that the positive results in the DST were not related with autonomous cortisol secretion.

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Publication Details

Journal
Clinical Endocrinology
Published
2025-11-26
DOI
https://doi.org/10.1111/cen.70065
Primary Topic
Adrenal Hormones and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Value of the Serum Dexamethasone Determination for the Diagnosis of Mild Autonomous Cortisol Secretion

Marta Rosillo, Antonio Rodríguez‐Poncelas, Ana María García Cano, Marta Araujo‐Castro et al.
Clinical Endocrinology
Adrenal Hormones and Disorders
article

Value of the Serum Dexamethasone Determination for the Diagnosis of Mild Autonomous Cortisol Secretion

Marta Rosillo, Antonio Rodríguez‐Poncelas, Ana María García Cano, Marta Araujo‐Castro, Eider Pascual‐Corrales, Imanol Madrid
article en

Abstract

Up to 4% of the patients with MACS diagnosis based on a DST > 1.8 µg/dl do not achieve enough dexamethasone levels to suppress the hypothalamic pituitary adrenal axis, suggesting that the positive results in the DST were not related with autonomous cortisol secretion.

Clinical Endocrinology
Instituto Cajal (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Hospital Universitario Ramón y Cajal (ES)
Instituto de Salud Carlos III
Openalex Percentile: Top 51%
Adrenal Hormones and Disorders
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