Gentamicin-loaded exosomes from IMMUNEPOTENT CRP enhance healing of infected diabetic wound in mice
Gentamicin-loaded exosomes derived from IMMUNEPOTENT CRP demonstrated enhanced antimicrobial activity and tissue regeneration in infected diabetic wounds. These findings support their potential as an effective and less invasive therapeutic strategy for diabetic foot ulcers by combining infection control and pro-regenerative and immunomodulatory effects.
Authors
- Diana Ginette Zárate-Triviño (ORCID: https://orcid.org/0000-0002-0852-8948)
- B. Martı́nez (ORCID: https://orcid.org/0000-0001-9879-7748)
- Gabriel Luna‐Bárcenas (ORCID: https://orcid.org/0000-0002-1162-6928)
- Paola Leonor García Coronado (ORCID: https://orcid.org/0000-0002-3705-9757)
- Pablo Zapata Benavides
- Cristina Rodrı́guez-Padilla (ORCID: https://orcid.org/0000-0001-5469-8449)
- Diana Hernández (ORCID: https://orcid.org/0000-0001-8906-0138)
- Moisés Armides Franco Molina
- Kenia Arisbe Moreno Amador
Institutions
- Universidad Autónoma de Nuevo León (MX)
- Instituto Tecnológico de Querétaro (MX)
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fphar.2025.1682468
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Consejo Nacional de Ciencia y Tecnología
- Instituto Tecnológico y de Estudios Superiores de Monterrey