Crystal structure of fluvoxamine maleate, (C <sub>15</sub> H <sub>22</sub> F <sub>3</sub> N <sub>2</sub> O <sub>2</sub> )(HC <sub>4</sub> H <sub>2</sub> O <sub>4</sub> )
Abstract The crystal structure of fluvoxamine hydrogen maleate has been solved and refined using synchrotron X-ray powder diffraction data and optimized using density functional theory techniques. Fluvoxamine maleate crystallizes in space group P2 1 /c (#14) with a = 21.6310(15), b = 5.3180(4), c = 19.5555(15) Å, β = 99.979(5)°, V = 2,215.48(25) Å 3 , and Z = 4 at 298 K. The crystal structure consists of alternating double layers of cations and anions parallel to the bc -plane. Hydrogen bonds link the layers of anions and cations parallel to the bc -plane. The powder pattern has been submitted to the International Centre for Diffraction Data for inclusion in the Powder Diffraction File ™ (PDF ® ).
Authors
- James A. Kaduk (ORCID: https://orcid.org/0000-0001-6610-541X)
- Thomas N. Blanton (ORCID: https://orcid.org/0000-0002-9506-7237)
- Anja Došen (ORCID: https://orcid.org/0000-0002-7700-8065)
Institutions
- Illinois Institute of Technology (US)
- International Centre for Diffraction Data (US)
- North Central College (US)
Publication Details
- Journal
- Powder Diffraction
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1017/s0885715625101061
- Primary Topic
- X-ray Diffraction in Crystallography
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada