Intestinal dysbiosis in critically ill patients: a case–control study of Enterobacteriaceae enrichment and reduced microbial diversity
ICU patients exhibit gut dysbiosis characterized by <i>Enterobacteriaceae</i> expansion and diversity loss, independent of sepsis status. These findings underscore the gut microbiome's role in critical illness and support exploring microbiota-targeted interventions (e.g., selective probiotics) to improve outcomes.
Authors
- Jinman Li (ORCID: https://orcid.org/0000-0003-0754-0758)
- Dan Wang
- Heng Tian
- Xiaolei Wang (ORCID: https://orcid.org/0000-0002-0183-5822)
- Xuan Zhou (ORCID: https://orcid.org/0009-0005-4015-5271)
- Huiyu Tian
- Lei Wang (ORCID: https://orcid.org/0000-0003-0734-7026)
Institutions
- Hebei Medical University (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fmed.2025.1680262
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00