Comparative analysis of scaffold-free tissue-engineered cartilage derived from different seed cells: <i>in vitro</i> and <i>in vivo</i> studies
ACs and CCs excelled in cartilage matrix synthesis; however, AC TEC exhibited phenotypic instability. CC TEC sustained a hyaline chondrocyte phenotype but had later connectivity issues, while BMSCs and SDSCs integrated better but primarily produced fibrous tissue.
Authors
- Dajiang Du (ORCID: https://orcid.org/0000-0002-4204-9721)
- Kaiwen Zheng (ORCID: https://orcid.org/0000-0003-3184-5375)
- Jiewei Chen (ORCID: https://orcid.org/0000-0002-5399-725X)
- Che Zheng
- Xiaofeng Liu (ORCID: https://orcid.org/0000-0002-4514-2016)
- Changqing Zhang (ORCID: https://orcid.org/0000-0002-7408-4126)
- Mengxin Xue
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Sixth People's Hospital (CN)
Publication Details
- Journal
- Stem Cells Translational Medicine
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1093/stcltm/szaf057
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67