CU Cilia – an application for image analysis by machine learning – reveals significance of cysteine cathepsin K activity for primary cilia of human thyroid epithelial cells
The results point to an elongation of primary cilia in the Odanacatib-treated Nthy-ori 3-1 thyroid epithelial cells, supporting the notion that cysteine cathepsin K activity is physiologically important not only in murine but also in human thyroid cells.
Authors
- Klaudia Brix (ORCID: https://orcid.org/0000-0002-4476-0357)
- Maren Rehders (ORCID: https://orcid.org/0000-0002-7854-0977)
- Petr Popov (ORCID: https://orcid.org/0000-0003-3745-7154)
- Alara Gaye Doğru (ORCID: https://orcid.org/0009-0007-7215-5035)
- João Gissoni
- Kseniia Alekseitseva
- Andrei Boiarov
Institutions
- University of Bremen (DE)
- Constructor University (DE)
- Constructing Excellence (GB)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fendo.2025.1588394
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00