Treatment with rapamycin prevents induction and expression of locomotor sensitization to synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV) in mice
Abolishment of locomotor sensitization to MDPV by rapamycin suggests that neuroadaptive changes underlying this phenomenon are dependent on the mTOR signaling and warrants further research on possible application of mTOR inhibitors in treatment of addiction.
Authors
- Jakub Wojcieszak (ORCID: https://orcid.org/0000-0001-9903-7206)
- K Kuçzyńska (ORCID: https://orcid.org/0000-0003-3103-5874)
- Jolanta B. Zawilska (ORCID: https://orcid.org/0000-0002-3696-2389)
Institutions
- Medical University of Lodz (PL)
Publication Details
- Journal
- Forensic Toxicology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1007/s11419-025-00749-w
- Primary Topic
- Forensic Toxicology and Drug Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniwersytet Łódzki