Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut–brain axis modulation in an Alzheimer’s disease rat model
MMF alleviates AD pathology through modulation of the gut microbiota and metabolic reprogramming, suggesting a promising microbiota-targeted strategy for AD prevention.
Authors
- Hui Xiao (ORCID: https://orcid.org/0000-0001-8260-7807)
- Mengwen Liu (ORCID: https://orcid.org/0000-0001-8006-5995)
- Yue Li (ORCID: https://orcid.org/0000-0002-6194-6065)
- Xuanshi Chen
- Yangyi Zhang (ORCID: https://orcid.org/0009-0009-8348-6424)
- Tuerxunayi Dawuti
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Urumqi 4th People's Hospital (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Pingjin Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fphar.2025.1695768
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Xinjiang