Comprehensive analysis and validation of the prognostic significance of cuproptosis-related genes in rectal adenocarcinoma
The prognostic system based on cuproptosis-related genes constructed in this study not only enhances the accuracy of survival prediction for rectal adenocarcinoma patients, revealing the potential role of cuproptosis in the tumor microenvironment and immune regulation, but also provides a new perspective for risk stratification and the selection of personalized treatment strategies, paving the way for precise oncology approaches in rectal adenocarcinoma.
Authors
- Zhicheng Pu
- Xinyu Gao (ORCID: https://orcid.org/0000-0003-4058-8024)
- Haoren Jing
- Shuocun Zhang
- Tianhao Li (ORCID: https://orcid.org/0000-0001-9500-6584)
- Mingqing Zhang (ORCID: https://orcid.org/0000-0003-4860-8173)
- Xipeng Zhang (ORCID: https://orcid.org/0009-0007-6259-1589)
Institutions
- Union Hospital (HK)
- Nankai University (CN)
- Tianjin First Center Hospital (CN)
- Tianjin Medical University General Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fcell.2025.1622829
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00