Single-cell transcriptomic analysis reveals a systemic immune dysregulation in intravenous immunoglobulin non-responsive Kawasaki disease

Our findings reveal the immune landscape in IVIG non-responsive KD and suggest potential targets for alternative therapies.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-11-27
DOI
https://doi.org/10.3389/fimmu.2025.1702290
Citations
2
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
Field-Weighted Citation Impact
4.01

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article

Single-cell transcriptomic analysis reveals a systemic immune dysregulation in intravenous immunoglobulin non-responsive Kawasaki disease

Y.-H. Chen, Minna Yang, Hongmao Wang, Qirui Li et al.
2 citations
Frontiers in Immunology
Kawasaki Disease and Coronary Complications
4.01
article

Single-cell transcriptomic analysis reveals a systemic immune dysregulation in intravenous immunoglobulin non-responsive Kawasaki disease

Y.-H. Chen, Minna Yang, Hongmao Wang, Qirui Li, Mingming Zhang, Chenhui Feng, Xiaohui Li
article en
2 citations

Abstract

Our findings reveal the immune landscape in IVIG non-responsive KD and suggest potential targets for alternative therapies.

Frontiers in ImmunologyVol. 16
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking University (CN), Capital Institute of Pediatrics (CN), Peking University People's Hospital (CN), Beijing Children’s Hospital (CN), Beijing Tsinghua Chang Gung Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 5%
Kawasaki Disease and Coronary Complications
4.01
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Single-cell transcriptomic analysis reveals a systemic immune dysregulation in intravenous immunoglobulin non-responsive Kawasaki disease — Y.-H. Chen, Minna Yang, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS