Penetrating the biofilm barrier: characterization of Escherichia phage vB_EcoS-TPF103dw and harnessing depolymerase to combat Shiga toxin-producing Escherichia coli O103 biofilm
The findings of this study provide insights into a novel <i>Tequintavirus</i> phage, vB_EcoS-TPF103dw, and demonstrate its genomic diversity, predicted depolymerase-encoding potential, stability under variable conditions, and antimicrobial efficacy against STEC O103 biofilms <i>in vitro</i>.
Authors
- Yen‐Te Liao (ORCID: https://orcid.org/0000-0002-4181-5308)
- Yujie Zhang (ORCID: https://orcid.org/0000-0002-4926-028X)
- Vivian C. H. Wu (ORCID: https://orcid.org/0000-0002-1525-1078)
- Leslie A. Harden
- David L. Campos
Institutions
- Agricultural Research Service (US)
- Western Regional Research Center (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fmicb.2025.1715907
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- U.S. Department of Agriculture
- Agricultural Research Service