Significant increase in calcification and ossification observed after the second relapse of low-grade myofibroblast sarcoma treated with radiotherapy followed by anlotinib and toripalimab: a case report

Based on this case report, palliative radiotherapy followed by anlotinib and toripalimab may yield an acceptable therapeutic effect while being associated with manageable treatment-related adverse events in LGMS patients experiencing two relapses, who have previously undergone targeted therapy using vascular endothelial growth factor receptor-tyrosine kinase inhibitors and have not received prior radiotherapy. Nevertheless, this hypothesis requires further validation through higher-level evidence-based medical research.