Hypertensive disorders of pregnancy increase neonatal cerebral regional tissue oxygen saturation in the early postnatal period: partial mediation by preterm birth
Maternal HDP is associated with elevated neonatal cerebral oxygenation and reduced cerebral oxygen extraction in the early postnatal period. These associations are partially mediated by preterm birth, which may be linked to impaired placental function in pregnancies complicated by HDP.
Authors
- Jun Tang (ORCID: https://orcid.org/0000-0003-4884-4248)
- Tao Xiong (ORCID: https://orcid.org/0000-0002-0408-1288)
- Junhong Wu
- Dengjun Liu
- Yao Zhang
- Dapeng Chen (ORCID: https://orcid.org/0000-0001-8412-581X)
- Tong Yang (ORCID: https://orcid.org/0009-0004-6780-7965)
- Yanxia Mao
- Yi Yang (ORCID: https://orcid.org/0009-0009-7760-333X)
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fcell.2025.1682675
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sichuan University
- Health Commission of Sichuan Province