Transfusion‐related adverse events in patients with restrictive or liberal transfusion strategy. An analysis of the <scp>MINT</scp> trial
The rate of major TRAE was low, albeit increased in the liberal transfusion arm proportional to the number of RBC units transfused. The higher rate of major TRAE in the liberal arm was not sufficient to offset the increased rates of myocardial infarction or death at 30 days observed in patients assigned to the restrictive transfusion arm.
Authors
- Philippe Gabríel Steg (ORCID: https://orcid.org/0000-0001-6896-2941)
- Robert O. Roswell (ORCID: https://orcid.org/0000-0003-4358-6534)
- Jay S. Raval (ORCID: https://orcid.org/0000-0001-9835-957X)
- Maria M. Brooks (ORCID: https://orcid.org/0000-0002-2030-7873)
- Paul C. Hébert (ORCID: https://orcid.org/0000-0002-0440-8586)
- Jeffrey L. Carson (ORCID: https://orcid.org/0000-0001-5466-2833)
- Kevin R. Bainey (ORCID: https://orcid.org/0000-0002-5458-4617)
- Shahab Ghafghazi (ORCID: https://orcid.org/0000-0001-5061-6119)
- François Roubille (ORCID: https://orcid.org/0000-0002-5288-9687)
- Lynne Uhl (ORCID: https://orcid.org/0000-0002-8868-7198)
- Marnie Bertolet (ORCID: https://orcid.org/0000-0002-5799-9033)
- Shaun G. Goodman (ORCID: https://orcid.org/0000-0001-8068-2440)
- Michael Goldfarb (ORCID: https://orcid.org/0000-0001-9790-1232)
- Arthur Bracey
- Renato D. Lópes (ORCID: https://orcid.org/0000-0003-2999-4961)
- Brandon M. Herbert (ORCID: https://orcid.org/0000-0003-3857-7422)
- John Hunter Alexander (ORCID: https://orcid.org/0000-0002-1444-2462)
- Christopher B. Fordyce (ORCID: https://orcid.org/0000-0002-4050-1518)
- Janek Manoj Senaratne (ORCID: https://orcid.org/0000-0002-2320-8926)
- Pedro Beraldo de Andrade (ORCID: https://orcid.org/0000-0003-3511-7375)
- Tabassome Simon
- Darrell J. Triulizi
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Vermont (US)
- St. Michael's Hospital (CA)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Hofstra University (US)
- University of Louisville (US)
- University of Alberta (CA)
- University of Pittsburgh (US)
- Duke University (US)
- Baylor College of Medicine (US)
- University of Toronto (CA)
- Université de Montpellier (FR)
- Jewish General Hospital (CA)
- Johnson University (US)
- Vancouver General Hospital (CA)
- Sorbonne Université (FR)
- Institute for Transfusion Medicine (US)
- Clinical Research Institute (US)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Canadian VIGOUR Centre (CA)
- Department of Health (TW)
- Bruyère (CA)
- Alliance nationale pour les sciences de la vie et de la santé (FR)
- McGill University (CA)
Publication Details
- Journal
- Transfusion
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1111/trf.70006
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Blood Services
- Agence Nationale de la Recherche
- Canadian Institutes of Health Research
- National Heart, Lung, and Blood Institute
- Institute of Circulatory and Respiratory Health