MIAs (Mirror Intracranial Aneurysms): symmetry-related patient risk or consequence of multiplicity?
MIAs were associated with higher patient-time rupture and SAH-specific mortality and greater lesion-level instability, but not with an independent per-aneurysm rupture hazard. The excess patient-level risk is largely explained by exposure (multiplicity); a symmetry-related effect remains plausible but unconfirmed. Larger, prospectively harmonised datasets are needed.
Authors
- Nitin Mukerji (ORCID: https://orcid.org/0000-0002-7427-9230)
- Lucie Ferguson (ORCID: https://orcid.org/0000-0002-9011-4313)
- Rosa Sun (ORCID: https://orcid.org/0000-0002-4979-1574)
- Bartlomiej Roj
Institutions
- Queen Elizabeth Hospital Birmingham (GB)
- Royal Victoria Infirmary (GB)
- James Cook University Hospital (GB)
- Southmead Hospital (GB)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1007/s00701-025-06716-z
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00