Comparative analysis of nerve fibers, PIEZO family and bone structural parameters difference surrounding dental implants
Peri-implant regions exhibited higher nerve fiber density and enhanced bone microarchitecture, suggesting neurogenic modulation of osseointegration dynamics. Mechanistically, the PIEZO family may mediate this neuro-osseous crosstalk during bone remodeling around implants. These findings offer novel perspectives on the mechanistic basis of peri-implant bone adaptation.
Authors
- Jianxiang Tao
- Jing Yu (ORCID: https://orcid.org/0000-0002-4899-0467)
- Qianqian Lu (ORCID: https://orcid.org/0000-0003-4640-9605)
- Yu Wei (ORCID: https://orcid.org/0000-0002-8875-213X)
Institutions
- Tongji University (CN)
- Shanghai Stomatological Hospital (CN)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s12903-025-07400-5
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00