Maintained improvement of outcomes related to skin clearance, itch, sleep and quality of life with baricitinib in adults with moderate-to-severe Atopic Dermatitis who were treated for up to 200 weeks in a randomized trial

AD symptom improvement was maintained up to Week 200 with baricitinib 4 mg. After down-titration, the vIGA-AD (0,1) response patient subgroup maintained clear or almost clear skin and itch response improvement. Clear or almost clear skin achievement may help identify optimal candidates for down-titration after 52 weeks of full-dose treatment.

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Publication Details

Journal
Journal of Dermatological Treatment
Published
2025-11-27
DOI
https://doi.org/10.1080/09546634.2025.2585244
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
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article

Maintained improvement of outcomes related to skin clearance, itch, sleep and quality of life with baricitinib in adults with moderate-to-severe Atopic Dermatitis who were treated for up to 200 weeks in a randomized trial

Journal of Dermatological Treatment
Dermatology and Skin Diseases
article

Maintained improvement of outcomes related to skin clearance, itch, sleep and quality of life with baricitinib in adults with moderate-to-severe Atopic Dermatitis who were treated for up to 200 weeks in a randomized trial

article en

Abstract

AD symptom improvement was maintained up to Week 200 with baricitinib 4 mg. After down-titration, the vIGA-AD (0,1) response patient subgroup maintained clear or almost clear skin and itch response improvement. Clear or almost clear skin achievement may help identify optimal candidates for down-titration after 52 weeks of full-dose treatment.

Journal of Dermatological TreatmentVol. 36(1)
Eli Lilly (United States) (US), University Hospital Augsburg (DE), Aarhus University Hospital (DK), Kyoto Prefectural University of Medicine (JP), Alessandro Manzoni Hospital (IT), Centre for Inflammation Research (GB), Hospital Universitari Germans Trias i Pujol (ES), Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 40%
Dermatology and Skin Diseases
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