Comparative effectiveness of sodium‐glucose cotransporter‐2 inhibitors and glucagon‐like peptide‐1 receptor agonists for incident dementia: A retrospective multicohort study
SGLT2i use was not associated with increased risk of dementia compared with GLP-1RAs in patients with T2DM. Further research is warranted to explore the effects of (newer) incretin-based (co-)agonists on cognitive outcomes.
Authors
- Christos Socrates Mantzoros (ORCID: https://orcid.org/0000-0003-3755-8158)
- Georgia Anastasiou (ORCID: https://orcid.org/0000-0003-4106-0563)
- S. Nagarajan
- Filippos Anagnostakis (ORCID: https://orcid.org/0000-0001-7374-8798)
- Michail Kokkorakis (ORCID: https://orcid.org/0000-0002-0027-5659)
Institutions
- Beth Israel Deaconess Medical Center (US)
- University Medical Center Groningen (NL)
- Harvard University (US)
- University of Groningen (NL)
- VA Boston Healthcare System (US)
- Laboratoire d’Imagerie Biomédicale (FR)
- University of Missouri–Kansas City (US)
- University of Bologna (IT)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1111/dom.70336
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00