Appendiceal Intussusception Secondary to Mantle Cell Lymphoma: A Report of a Rare Case

Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma that can involve the gastrointestinal (GI) tract. Appendiceal involvement, however, is highly uncommon. Appendiceal intussusception is a rare entity, accounting for only a small fraction of appendicectomy findings. We present a rare case of a 68-year-old male who developed appendiceal intussusception secondary to mantle cell lymphoma, diagnosed following laparoscopic right hemicolectomy. To the best of our knowledge, this is the first reported case of MCL manifesting with appendiceal intussusception. This report emphasises the significance of considering lymphoproliferative disorders in elderly patients presenting with persistent right lower quadrant pain and imaging suggestive of intussusception.

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Publication Details

Journal
Cureus
Published
2025-11-27
DOI
https://doi.org/10.7759/cureus.97918
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Appendiceal Intussusception Secondary to Mantle Cell Lymphoma: A Report of a Rare Case

Francis Asomah, Nariyoshi Miyata
Cureus
Intraperitoneal and Appendiceal Malignancies
article

Appendiceal Intussusception Secondary to Mantle Cell Lymphoma: A Report of a Rare Case

Francis Asomah, Nariyoshi Miyata
article en

Abstract

Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma that can involve the gastrointestinal (GI) tract. Appendiceal involvement, however, is highly uncommon. Appendiceal intussusception is a rare entity, accounting for only a small fraction of appendicectomy findings. We present a rare case of a 68-year-old male who developed appendiceal intussusception secondary to mantle cell lymphoma, diagnosed following laparoscopic right hemicolectomy. To the best of our knowledge, this is the first reported case of MCL manifesting with appendiceal intussusception. This report emphasises the significance of considering lymphoproliferative disorders in elderly patients presenting with persistent right lower quadrant pain and imaging suggestive of intussusception.

CureusVol. 17(11)
Mount Auburn Hospital (US), Mount Medical Centre (AU)
Openalex Percentile: Top 44%
Intraperitoneal and Appendiceal Malignancies
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Appendiceal Intussusception Secondary to Mantle Cell Lymphoma: A Report of a Rare Case — Francis Asomah, Nariyoshi Miyata · Cureus (2025) | TGRS Research Map | TGRS