Repurposing Agents as Anti-Infective Therapeutics to Aid in the Treatment of Candida auris Infections

These findings support the potential clinical utility of repurposing existing agents, such as Ethyl Pyruvate or EDTA, for systemic <i>C. auris</i> infections, or hypochlorous acid for <i>C. auris</i> wound infections. Yet, further studies are needed to optimize dosing parameters and evaluate in vivo efficacy and tolerability.

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Publication Details

Journal
Infectious Disease Reports
Published
2025-11-27
DOI
https://doi.org/10.3390/idr17060144
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00
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article

Repurposing Agents as Anti-Infective Therapeutics to Aid in the Treatment of Candida auris Infections

James B. Doub, Nazary Nebeluk
Infectious Disease Reports
Antifungal resistance and susceptibility
article

Repurposing Agents as Anti-Infective Therapeutics to Aid in the Treatment of Candida auris Infections

James B. Doub, Nazary Nebeluk
article en

Abstract

These findings support the potential clinical utility of repurposing existing agents, such as Ethyl Pyruvate or EDTA, for systemic <i>C. auris</i> infections, or hypochlorous acid for <i>C. auris</i> wound infections. Yet, further studies are needed to optimize dosing parameters and evaluate in vivo efficacy and tolerability.

Infectious Disease ReportsVol. 17(6)
University of Maryland, Baltimore (US)
Openalex Percentile: Top 57%
Antifungal resistance and susceptibility
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Repurposing Agents as Anti-Infective Therapeutics to Aid in the Treatment of Candida auris Infections — James B. Doub, Nazary Nebeluk · Infectious Disease Reports (2025) | TGRS Research Map | TGRS