Transplacental Antimicrobial Antibodies and Childhood Asthma: Maternal Nativity as an Upstream Factor
In this US prospective birth cohort, maternal transplacental IgG reactivity to four microbes (A. actinomycetemcomitans, H. pylori, S. flexneri and T. parva) was associated with a lower risk of childhood asthma, and partly explains the lower risk of asthma in children of mothers born outside the US.
Authors
- William R. Morgenlander (ORCID: https://orcid.org/0000-0001-7205-3732)
- Hongkai Ji (ORCID: https://orcid.org/0000-0002-6480-0141)
- Ni Zhao (ORCID: https://orcid.org/0000-0002-7762-3949)
- Kari Christine Nadeau (ORCID: https://orcid.org/0000-0002-2146-2955)
- August Jernbom Falk (ORCID: https://orcid.org/0000-0002-7773-1851)
- Xiumei Hong (ORCID: https://orcid.org/0000-0003-3992-1918)
- Colleen Pearson (ORCID: https://orcid.org/0000-0001-6669-6774)
- Pamela A. Frischmeyer‐Guerrerio (ORCID: https://orcid.org/0000-0003-2259-5546)
- William G. Adams (ORCID: https://orcid.org/0000-0002-5330-0010)
- H. Benjamin Larman (ORCID: https://orcid.org/0000-0001-7863-196X)
- Julia W. Angkeow (ORCID: https://orcid.org/0009-0002-8274-1859)
- Shuai Li (ORCID: https://orcid.org/0000-0002-8696-8594)
- Xiaobin Wang (ORCID: https://orcid.org/0000-0003-4451-302X)
- Guoying Wang (ORCID: https://orcid.org/0000-0002-9423-8946)
- M Thakar
Institutions
- Boston University (US)
- Boston Medical Center (US)
- Massachusetts Department of Public Health (US)
- Harvard University (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Science for Life Laboratory (SE)
- National Institute of Allergy and Infectious Diseases (US)
- KTH Royal Institute of Technology (SE)
Publication Details
- Journal
- Allergy
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1111/all.70167
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00