Simulation-based activated clotting time targeting for cardiopulmonary bypass in patients with antiphospholipid syndrome: two case reports
Preoperative ACT simulation using patient serum offers a practical, accessible, and individualized method for guiding anticoagulation therapy in patients with APS undergoing cardiac surgery. This technique may enhance perioperative safety in resource-limited settings, and warrants further validation in larger cohorts.
Authors
- Yosuke Saito (ORCID: https://orcid.org/0000-0002-4791-426X)
- Hiromi Fujii (ORCID: https://orcid.org/0000-0003-0155-3873)
- Yoichiro Machida
- Hiroaki Hata (ORCID: https://orcid.org/0000-0002-8902-0256)
- Y Kamikawa
- Hirotaka Inaba (ORCID: https://orcid.org/0000-0002-2437-6841)
Institutions
- Juntendo University Urayasu Hospital (JP)
- Social Insurance Saitama Chuo Hospital (JP)
Publication Details
- Journal
- General Thoracic and Cardiovascular Surgery Cases
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s44215-025-00235-0
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00