Application of Probe-Capture metagenomics in rabies diagnosis
pc-mNGS demonstrates potential as a rapid, economical diagnostic tool capable of detecting RabV in specimens with low viral loads-such as blood and cerebrospinal fluid-from both exposed and unexposed individuals. Simultaneous identification of additional pathogens further supports its diagnostic utility.
Authors
- Panyan Liu
- Zhenfeng Deng (ORCID: https://orcid.org/0000-0001-5226-9392)
- J PENG (ORCID: https://orcid.org/0009-0009-2799-5443)
- Jingmao Lao
- Peitang Huang
- Yuhang Wang (ORCID: https://orcid.org/0009-0008-9915-9121)
- Feifan Wu (ORCID: https://orcid.org/0000-0003-0039-5383)
- Yuanli Wang (ORCID: https://orcid.org/0000-0002-9685-1859)
Institutions
- Beibu Gulf University (CN)
- Kingmed Diagnostics (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s12985-025-03029-6
- Primary Topic
- Rabies epidemiology and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00