Therapeutic potential of ultrasound for spinal cord injury

Spinal cord injury is a debilitating condition that often results in permanent impairments in motor, sensory, and autonomic functions. The potential for treating spinal cord injury with ultrasound is increasingly being recognized. Ultrasound addresses several key aspects of spinal cord injury, including promoting nerve healing by creating a regenerative environment, attenuating inflammation, and managing secondary complications. While preclinical studies show encouraging results, further translational efforts are necessary to adapt these therapies for clinical use. Insights gained from transcranial ultrasound applications, such as transducer selection, anatomical considerations, and pre-treatment planning, can provide valuable guidance for optimizing ultrasound treatments for spinal cord injury. This literature review highlights the exciting potential of ultrasound therapy in spinal cord injury research and the importance of refining treatment parameters and strategies for successful clinical translation.

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Publication Details

Journal
Neural Regeneration Research
Published
2025-11-25
DOI
https://doi.org/10.4103/nrr.nrr-d-25-00978
Primary Topic
Ultrasound and Hyperthermia Applications
Type
article
Field-Weighted Citation Impact
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article

Therapeutic potential of ultrasound for spinal cord injury

Sachin Thakur, Darren M. Svirskis, Brad Raos, Maria Asplund et al.
Neural Regeneration Research
Ultrasound and Hyperthermia Applications
article

Therapeutic potential of ultrasound for spinal cord injury

Sachin Thakur, Darren M. Svirskis, Brad Raos, Maria Asplund, Ederlyn Perolina
article en

Abstract

Spinal cord injury is a debilitating condition that often results in permanent impairments in motor, sensory, and autonomic functions. The potential for treating spinal cord injury with ultrasound is increasingly being recognized. Ultrasound addresses several key aspects of spinal cord injury, including promoting nerve healing by creating a regenerative environment, attenuating inflammation, and managing secondary complications. While preclinical studies show encouraging results, further translational efforts are necessary to adapt these therapies for clinical use. Insights gained from transcranial ultrasound applications, such as transducer selection, anatomical considerations, and pre-treatment planning, can provide valuable guidance for optimizing ultrasound treatments for spinal cord injury. This literature review highlights the exciting potential of ultrasound therapy in spinal cord injury research and the importance of refining treatment parameters and strategies for successful clinical translation.

Neural Regeneration Research
University of Auckland (NZ), Auckland University of Technology (NZ), Chalmers University of Technology (SE)
Openalex Percentile: Top 64%
Ultrasound and Hyperthermia Applications
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Therapeutic potential of ultrasound for spinal cord injury — Sachin Thakur, Darren M. Svirskis, et al. · Neural Regeneration Research (2025) | TGRS Research Map | TGRS