Patient selection and outcome in low-grade glioma surgery
We found that surgical selection was associated with age, tumor size, and location. The median EOR in a population-based cohort was 83%, with age and tumor biology being significant predictors. EOR did not correlate with higher risks or worse neurological outcomes. We provide an epidemiological perspective demonstrating a variation in surgical selection and techniques reflecting persistent controversy in dLGG management.
Authors
- Klas Holmgren (ORCID: https://orcid.org/0000-0002-8611-1304)
- Gregor Tomasevic (ORCID: https://orcid.org/0009-0004-5838-8471)
- Eddie de Dios
- Alba Corell (ORCID: https://orcid.org/0000-0002-6329-2392)
- Alice Neimantaite (ORCID: https://orcid.org/0009-0004-0293-6707)
- Maria Zetterling (ORCID: https://orcid.org/0000-0003-4590-7063)
- Øystein Vesterli Tveiten (ORCID: https://orcid.org/0000-0002-2107-9251)
- Ole Solheim (ORCID: https://orcid.org/0000-0002-5954-4817)
- Sasha Gulati (ORCID: https://orcid.org/0000-0003-3072-5697)
- Tora Dunås (ORCID: https://orcid.org/0000-0002-5911-9511)
- Margret Jensdottir (ORCID: https://orcid.org/0000-0002-6127-326X)
- Alexander Fletcher‐Sandersjöö (ORCID: https://orcid.org/0000-0002-3558-3045)
- Tomás Gómez Vecchio (ORCID: https://orcid.org/0009-0000-6765-0428)
- Björn Sjögren (ORCID: https://orcid.org/0000-0001-9466-9829)
- Peter Milos (ORCID: https://orcid.org/0000-0002-8951-0263)
- Henrietta Nittby Redebrandt
- Rickard L. Sjöberg (ORCID: https://orcid.org/0000-0002-8258-0699)
- Ruby Mahesparan
- Asgeir Store Jakola (ORCID: https://orcid.org/0000-0002-2860-9331)
- Francesco Latini (ORCID: https://orcid.org/0000-0002-4702-526X)
- Jiří Bártek (ORCID: https://orcid.org/0000-0003-2013-7525)
- Lars Kjelsberg Pedersen (ORCID: https://orcid.org/0000-0001-5332-6897)
Institutions
- Linköping University (SE)
- University Hospital of North Norway (NO)
- Karolinska University Hospital (SE)
- Uppsala University Hospital (SE)
- Norwegian University of Science and Technology (NO)
- Haukeland University Hospital (NO)
- Sahlgrenska University Hospital (SE)
- Copenhagen University Hospital (DK)
- Karolinska Institutet (SE)
- University Hospital of Umeå (SE)
- St Olav's University Hospital (NO)
- Skåne University Hospital (SE)
- Linköping University Hospital (SE)
- University of Bergen (NO)
- University of Gothenburg (SE)
- Umeå University (SE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.3389/fonc.2025.1703756
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00