There is not one Parkinson’s disease, nor is there one cure

Parkinson’s disease (PD) is not a single disease but a diverse syndrome with varied biological mechanisms, symptoms, and trajectories. Outdated stereotypes and one-size-fits-all approaches to disease-modifying therapies have stymied progress in research, and public understanding. Emerging efforts in biomarker-based subtyping and precision medicine emphasize personalized methods tailored to an individual’s biology. Progress requires research includes all segments of the patient population and the understanding that the cure is personalized.

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Publication Details

Journal
npj Parkinson s Disease
Published
2025-11-27
DOI
https://doi.org/10.1038/s41531-025-01183-w
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

There is not one Parkinson’s disease, nor is there one cure

S. Bowen
npj Parkinson s Disease
Parkinson's Disease Mechanisms and Treatments
article

There is not one Parkinson’s disease, nor is there one cure

S. Bowen
article en

Abstract

Parkinson’s disease (PD) is not a single disease but a diverse syndrome with varied biological mechanisms, symptoms, and trajectories. Outdated stereotypes and one-size-fits-all approaches to disease-modifying therapies have stymied progress in research, and public understanding. Emerging efforts in biomarker-based subtyping and precision medicine emphasize personalized methods tailored to an individual’s biology. Progress requires research includes all segments of the patient population and the understanding that the cure is personalized.

npj Parkinson s DiseaseVol. 11(1)
University of North Carolina at Chapel Hill (US), National Academy of Governance (MN), Patient Advocate Foundation (US)
Openalex Percentile: Top 49%
Parkinson's Disease Mechanisms and Treatments
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There is not one Parkinson’s disease, nor is there one cure — S. Bowen · npj Parkinson s Disease (2025) | TGRS Research Map | TGRS