Comparative analysis of general anaesthesia with and without dexmedetomidine in emergence agitation

Emergence agitation (EA) is a common concern in maxillofacial surgeries under general anaesthesia. Therefore, it is of interest to evaluate the role of intraoperative dexmedetomidine infusion in its prevention. Ninety ASA I-II adult patients were randomized into two groups general anaesthesia alone (Group A) and general anaesthesia with dexmedetomidine (Group B). Dexmedetomidine significantly reduced the incidence and severity of EA (p <l0.001) improved sedation scores and provided better hemodynamic stability without increasing pain, nausea or vomiting. Bradycardia was more frequent in the dexmedetomidine group but also manageable making it a safe and effective adjuvant for enhancing recovery quality.

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Bioinformation
Published
2025-11-15
DOI
https://doi.org/10.6026/973206300214231
Primary Topic
Anesthesia and Sedative Agents
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article
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article

Comparative analysis of general anaesthesia with and without dexmedetomidine in emergence agitation

Shalini Jain
Bioinformation
Anesthesia and Sedative Agents
article

Comparative analysis of general anaesthesia with and without dexmedetomidine in emergence agitation

Shalini Jain
article en

Abstract

Emergence agitation (EA) is a common concern in maxillofacial surgeries under general anaesthesia. Therefore, it is of interest to evaluate the role of intraoperative dexmedetomidine infusion in its prevention. Ninety ASA I-II adult patients were randomized into two groups general anaesthesia alone (Group A) and general anaesthesia with dexmedetomidine (Group B). Dexmedetomidine significantly reduced the incidence and severity of EA (p <l0.001) improved sedation scores and provided better hemodynamic stability without increasing pain, nausea or vomiting. Bradycardia was more frequent in the dexmedetomidine group but also manageable making it a safe and effective adjuvant for enhancing recovery quality.

BioinformationVol. 21(11)
Mahatma Gandhi Memorial Medical College (IN)
Openalex Percentile: Top 45%
Anesthesia and Sedative Agents
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