Molecular epidemiological investigation of the carbapenemase-producing Enterobacterales isolates in Okayama prefecture, Japan

We investigated the genetic characteristics of non-IMP type carbapenemase-producing Enterobacterales isolates detected in Japan. The isolates were found to carry diverse plasmids with high sequence similarity to those previously reported in other countries, underscoring the critical imperative for comprehensive nationwide epidemiological surveillance for the silent pandemic of the nightmare pathogen.

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Publication Details

Journal
Diagnostic Microbiology and Infectious Disease
Published
2025-11-28
DOI
https://doi.org/10.1016/j.diagmicrobio.2025.117209
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Molecular epidemiological investigation of the carbapenemase-producing Enterobacterales isolates in Okayama prefecture, Japan

Koji Iio, Kazuyoshi Gotoh, Hideharu Hagiya, Fumio Otsuka et al.
Diagnostic Microbiology and Infectious Disease
Antibiotic Resistance in Bacteria
article

Molecular epidemiological investigation of the carbapenemase-producing Enterobacterales isolates in Okayama prefecture, Japan

Koji Iio, Kazuyoshi Gotoh, Hideharu Hagiya, Fumio Otsuka, Yasurou Inoue, Mayu Sato, Shinnosuke Fukushima, Shuma Tsuji, Tomoko Fudeyasu, Sayaka Sakita
article en

Abstract

We investigated the genetic characteristics of non-IMP type carbapenemase-producing Enterobacterales isolates detected in Japan. The isolates were found to carry diverse plasmids with high sequence similarity to those previously reported in other countries, underscoring the critical imperative for comprehensive nationwide epidemiological surveillance for the silent pandemic of the nightmare pathogen.

Diagnostic Microbiology and Infectious DiseaseVol. 114(3)
Okayama University (JP), Okayama University Hospital (JP), Tsuyama Chuo Hospital (JP), Okayama Prefecture (JP), Okayama Rosai Hospital (JP)
Openalex Percentile: Top 68%
Antibiotic Resistance in Bacteria
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Molecular epidemiological investigation of the carbapenemase-producing Enterobacterales isolates in Okayama prefecture, Japan — Koji Iio, Kazuyoshi Gotoh, et al. · Diagnostic Microbiology and Infectious Disease (2025) | TGRS Research Map | TGRS