Length of stay, duration of mechanical ventilation, mortality, and acute kidney injury in acute respiratory failure requiring endotracheal intubation
Among all investigated outcome measures, COVID-19, Ppeak, and RR were strongly associated with all the endpoints studied, suggesting that proper interventions involving the modifiable respiratory parameters Ppeak and RR could improve the overall outcome in these patients. A novel finding of this study was the relationship between RR and AKI, which is worthy of further investigation. Future studies may explore the clinical interpretation of these findings to improve outcomes in critically ill patients with acute respiratory failure.
Authors
- Panagiotis Papamichalis (ORCID: https://orcid.org/0000-0001-7296-419X)
- Asimina Valsamaki
- Konstantinos Mantzarlis (ORCID: https://orcid.org/0000-0002-2453-5398)
- Apostolia-Lemonia Skoura
- Antonio Artigas (ORCID: https://orcid.org/0000-0002-8029-1017)
- Michail Papamichalis (ORCID: https://orcid.org/0000-0002-4994-7743)
- Achilleas Chovas
- Periklis Katsiafylloudis
- Maria Xanthoudaki
- A KOUKOULIS
- Evangelia Papapostolou (ORCID: https://orcid.org/0000-0003-0550-9343)
- Sophia K Papathanasiou (ORCID: https://orcid.org/0009-0005-3595-3738)
- Katerina G Oikonomou
- Gkreta Mavrommati
- Panagiotis Giannakos
- Dimitrios Plageras
Institutions
- University of Thessaly (GR)
- University Hospital of Larissa (GR)
Publication Details
- Journal
- World Journal of Critical Care Medicine
- Published
- 2025-11-28
- DOI
- https://doi.org/10.5492/wjccm.v14.i4.103708
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00