Photodynamic therapy for extramammary paget’s disease: A retrospective analysis of 15 cases

PDT shows promising results as a non-invasive treatment option for EMPD, providing a favorable balance between effectiveness and safety. The short-term efficacy of photodynamic therapy is highly encouraging; however, its long-term efficacy remains suboptimal. For patients who are unwilling or unsuitable for surgery, photodynamic therapy is a viable alternative. Although photodynamic therapy can achieve complete remission of lesions in some patients, its cure rate is relatively low, and there is a risk of recurrence. Further studies with larger sample sizes are needed to confirm these findings and investigate long-term outcomes.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-27
DOI
https://doi.org/10.1016/j.pdpdt.2025.105301
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
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article

Photodynamic therapy for extramammary paget’s disease: A retrospective analysis of 15 cases

Lingling Sun, Xiaohua Chen, Feng Chen, LI Li-bo et al.
Photodiagnosis and Photodynamic Therapy
Cancer and Skin Lesions
article

Photodynamic therapy for extramammary paget’s disease: A retrospective analysis of 15 cases

Lingling Sun, Xiaohua Chen, Feng Chen, LI Li-bo, Xiaojun Cai, Zeng Ruifang
article en

Abstract

PDT shows promising results as a non-invasive treatment option for EMPD, providing a favorable balance between effectiveness and safety. The short-term efficacy of photodynamic therapy is highly encouraging; however, its long-term efficacy remains suboptimal. For patients who are unwilling or unsuitable for surgery, photodynamic therapy is a viable alternative. Although photodynamic therapy can achieve complete remission of lesions in some patients, its cure rate is relatively low, and there is a risk of recurrence. Further studies with larger sample sizes are needed to confirm these findings and investigate long-term outcomes.

Photodiagnosis and Photodynamic TherapyVol. 56
TCM-Intigrated Cancer Center of Southern Medical University (CN), Southern Medical University (CN)
Openalex Percentile: Top 40%
Cancer and Skin Lesions
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