Vascular aging mediates the association between atherogenic lipid profiles and depression: survey-weighted evidence from NHANES 2005–2020
Atherogenic lipid phenotypes were linked to depressive symptoms, with vascular aging explaining part of this association, especially in women. These findings support vascular aging as a pathway connecting dyslipidemia to mood and motivate longitudinal studies targeting lipid quality and large-artery stiffness.
Authors
- Mairepaiti Halimulati
- Hanyue Zhang (ORCID: https://orcid.org/0000-0003-1947-3310)
- Liu Ya (ORCID: https://orcid.org/0009-0004-2229-2005)
- Lei Peng (ORCID: https://orcid.org/0000-0003-4315-4897)
Institutions
- Heidelberg University (DE)
- Frederiksberg Hospital (DK)
- Southwest Medical University (CN)
- The University of Texas at Austin (US)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1016/j.jad.2025.120749
- Primary Topic
- Cardiac Health and Mental Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00